The Senate seat was vacated after the death of the PPP’s veteran Senator Taj Haider.
Voting started at 9:00 am and will continue without a break until 4:00 pm in the Sindh Assembly Hall.
PPP has awarded a ticket to Waqar Mehdi, while the MQM-P fielded Nighat Mirza as its candidate to contest the election.
The People’s Party, which is ruling party in Sindh, enjoys majority in provincial legislature with 116 members strength, MQM-P has 36 members in the house.
Meanwhile, the PTI-backed independent members have announced a boycott of the election.
The PTI’s parliamentary leader in the assembly, Shabbir Ali Qureshi, has announced that none of their members will take part in the vote.
Earlier, the Election Commission of Sindh had said that it had completed all arrangements for the polling.
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